"Let's fight hate & ignorance with love for trans teens, who are already facing steep odds and who need our support to grow and THRIVE," Dunham said.
The Girls creator has also pledged to match donations to the center up to $50,000.
The issue is a personal one for Dunham, whose younger sibling is gender non-confirming. Grace Dunham came out in 2016 saying, "I'm not a woman, but I'm not a man," as they stripped down for StyleLikeU's online video series, "The What's Underneath Project."
The Ruth Ellis Center is one of only four organizations in the U.S. that provides shelter and services to at-risk LGBT youth. Click here to donate.
I watched the Kid Rock Turning Point USA halftime show so you don't have to
Opinion: "I have no problem with lip syncing, but you'd think the side that hates drag queens so much would have a little more shame about it," writes Ryan Adamczeski.