The Egyptian goddess, also worshipped by Greeks, is known for solving a gender identity issue of yore. Iphis was born female but raised male by his mother, who concealed the truth because her husband wanted a male heir. Ultimately, Iphis fell in love with Ianthe, a woman, and was betrothed to her. Before the wedding, Iphis prayed in the Temple of Isis for a solution, and voila! she became a he. As noted on Owlcation, this may have been a heterosexual ending, but the love story was laced with LGBT themes. Above: Isis (seated right) welcoming the Greek heroine Io as she is borne into Egypt on the shoulders of the personified Nile, as depicted in a Roman wall painting from Pompeii.