• 28. Neil Patrick Harris
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Named one of last year's Entertainers of the Year by Entertainment Weekly, Out cover guy Harris could do no wrong wherever he showed up -- owning every scene on How I Met Your Mother (for which he's been nominated for two Emmys and a Golden Globe), on the big screen in Harold & Kumar Escape From Guantanamo Bay, and headlining Joss Whedon's internet event of 2008, Dr. Horrible's Sing-Along Blog, a series that got 1,000 hits per second when it debuted and earned more than $2 million on iTunes in a few weeks. This summer, Harris returns to the stage, starring in L.A. Theatre Works' production of The Importance of Being Earnest.